The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 16, 2024

Filed:

Dec. 30, 2020
Applicant:

Rutgers, the State University of New Jersey, New Brunswick, NJ (US);

Inventors:

Ki-Bum Lee, Piscataway, NJ (US);

Hudifah Rabie, Piscataway, NJ (US);

Nicholas Pasquale, Piscataway, NJ (US);

Yixiao Zhang, Piscataway, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C09K 11/08 (2006.01); A61K 31/203 (2006.01); A61K 49/00 (2006.01); B82Y 5/00 (2011.01); B82Y 40/00 (2011.01); C09K 11/02 (2006.01); C12N 5/074 (2010.01); C12N 15/115 (2010.01);
U.S. Cl.
CPC ...
C09K 11/0833 (2013.01); A61K 31/203 (2013.01); A61K 49/0013 (2013.01); C09K 11/02 (2013.01); C12N 5/0696 (2013.01); C12N 15/115 (2013.01); B82Y 5/00 (2013.01); B82Y 40/00 (2013.01); C12N 2310/16 (2013.01); C12N 2500/05 (2013.01); C12N 2506/03 (2013.01); C12N 2529/10 (2013.01);
Abstract

Disclosed herein are embodiments of a composition comprising at least three layers. Layers one and two each either comprises a sensitizer or an emitter, typically a metal ion or a dye, and the third layer may or may not comprise a sensitizer or emitter. Upon exposure to light, such as infrared light, the composition produces visible and/or UV light. The composition may further comprise a capping moiety, a therapeutic agent, an uptake enhancer, a detection moiety that binds to a desired target, a quenching moiety, or a combination thereof. The composition may be a particle, such as a nanoparticle, or it may be a planar composition. Also disclosed are embodiments of a method for using the composition, including, but not limited to, a method for delivering a therapeutic agent, or a method for detecting a target, such as a biological target.


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