The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2024
Filed:
Aug. 29, 2022
Ambrx, Inc., La Jolla, CA (US);
Richard S Barnett, San Marcos, CA (US);
Nickolas Knudsen, Escondido, CA (US);
Ying Sun, San Diego, CA (US);
Sandra Biroc, Alameda, CA (US);
Timothy Buss, Carlsbad, CA (US);
Tsotne Javahishvili, Del Mar, CA (US);
Damien Bresson, San Diego, CA (US);
Shailaja Srinagesh, San Diego, CA (US);
Amha Hewet, San Diego, CA (US);
Jason Pinkstaff, Carlsbad, CA (US);
Abstract
This invention relates to anti-CD70 antibodies and antibody drug conjugates comprising at least one non-naturally-encoded amino acid. Disclosed herein are αCD70 antibodies with one or more non-naturally encoded amino acids and further disclosed are antibody drug conjugates wherein the αCD70 antibodies of the invention are conjugated to one or more toxins. Further disclosed are methods for using such non-natural amino acid antibody drug conjugates, including therapeutic, diagnostic, and other biotechnology uses.