The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2024
Filed:
May. 31, 2019
Biogen MA Inc., Cambridge, MA (US);
Janine Lisa Ferrant-Orgettas, Gloucester, MA (US);
Robert Blake Pepinsky, Arlington, MA (US);
Ellen Duggan Cahir-McFarland, Newtonville, MA (US);
Nadia Giselle D'Lima, Cambridge, MA (US);
Joseph Walter Arndt, Swampscott, MA (US);
Karl John Mortley Hanf, Billerica, MA (US);
Thomas Owen Cameron, Cambridge, MA (US);
Ellen Garber Stark, Cambridge, MA (US);
Biogen MA Inc., Cambridge, MA (US);
Abstract
The invention relates to anti-VLA-4 antibodies and binding fragments thereof. The invention further includes polynucleotides encoding said antibodies and binding fragments thereof and methods of manufacturing said antibodies and binding fragments thereof. The invention further includes methods of treating patients suffering from multiple sclerosis and/or epilepsy by administration of said antibodies and binding fragments thereof. The invention further includes methods of reducing the susceptibility to scrambling of a recombinant anti-alpha 4 antibody or a binding fragment thereof.