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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12037382 B1

PDFFull Text
Date of Patent:
Jul. 16, 2024

Filed:

Feb. 05, 2019

Inverse agonistic anti-us28 antibodies

Applicant:

Stichting VU, Amsterdam, NL;

Inventors:

Martine Joyce Smit, Amstrerdan, NL;

Raimond Heukers, Utrecht, NL;

Timo Werner Marcella De Groof, Ghent, BE;

Tian Shu Fan, Leiden, NL;

Raymond Henry De Wit, Amsterdam, NL;

Assignee:

Stichting VU, Amsterdam, NL;

Attorney:

Banner & Witcoff, Ltd.

Primary Examiner:

Michail A Belyavskyi

Int. Cl.
CPC ...
A61K 47/68 (2017.01); A61K 41/00 (2020.01); C07K 16/08 (2006.01); C07K 16/18 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C07K 16/085 (2013.01); A61K 41/0057 (2013.01); A61K 47/6839 (2017.08); A61K 47/6865 (2017.08); C07K 16/18 (2013.01); G01N 33/57492 (2013.01); C07K 2317/31 (2013.01); C07K 2317/565 (2013.01); C07K 2317/569 (2013.01); C07K 2317/92 (2013.01); G01N 2333/045 (2013.01);
Abstract

The invention relates to a novel class of antagonistic and inverse agonistic anti-US28 antibodies, more specifically to single heavy chain variable domain antibodies (VHH) and variants and modifications thereof. The invention further relates to methods for producing these antibodies and to the use of the antibodies in methods for diagnostic and therapeutic purposes, especially for treatment of an individual suffering from a CMV-positive tumor such as glioblastoma.

Find Patent Forward Citations

Smit, Martine. (2024). Inverse agonistic anti-us28 antibodies (U.S. Patent No. 12037382). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12037382

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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