The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2024
Filed:
Dec. 22, 2021
Applicant:
Plasma Technologies, Llc, Charleston, SC (US);
Inventors:
Eugene Zurlo, Charleston, SC (US);
Dennis Curtin, Charleston, SC (US);
Klaus Peter Radtke, Apex, NC (US);
Ryan Dorfman, Essex, VT (US);
Matthew Whelihan, Colchester, VT (US);
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/22 (2006.01); B01D 15/36 (2006.01); C07K 1/16 (2006.01); C07K 1/18 (2006.01); C07K 1/20 (2006.01);
U.S. Cl.
CPC ...
C07K 1/22 (2013.01); B01D 15/362 (2013.01); B01D 15/363 (2013.01); C07K 1/165 (2013.01); C07K 1/18 (2013.01); C07K 1/20 (2013.01);
Abstract
Systems and methods are described in which proteins are isolated from complex solution using successive chromatographic separations that retain the protein of interest in the flow-through. At least one of the chromatography media used is selected to be capable of interacting with both contaminants and the protein of interest, however capacity of this media is selected such that the protein of interest is displaced and remains in the flow-through.