The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2024
Filed:
Aug. 30, 2023
Deciduous Therapeutics, Inc., San Francisco, CA (US);
Matthew Duncton, Las Vegas, NV (US);
Thomas Bobinski, San Diego, CA (US);
Robin Mansukhani, San Francisco, CA (US);
Deciduous Therapeutics, Inc., San Francisco, CA (US);
Abstract
Compounds as depicted below and structural analogues thereof for activating invariant natural killer T cells (iNKT) cells are provided. Such compounds may be used to activate iNKT cells and induce an increase in the production of one or more cytokines, such as IFNγ, IL-2, IL-4, IL-6 and TNFα. Activated iNKT cells may be used to selectively reduce the presence of or eliminate inflammatory senescent cells, such as senescent cells having an inflammatory secretome (SASP). Also provided are pharmaceutical compositions comprising such compounds.