The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2024
Filed:
May. 03, 2019
Applicant:
Saint Louis University, St. Louis, MO (US);
Inventors:
Christopher Kent Arnatt, Manchester, MO (US);
Chelsea DeLeon, St. Louis, MO (US);
Assignee:
Saint Louis University, St. Louis, MO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 407/04 (2006.01); A61K 31/135 (2006.01); A61K 31/136 (2006.01); A61K 31/137 (2006.01); A61K 45/06 (2006.01); C07D 213/38 (2006.01); C07D 307/52 (2006.01); C07D 333/20 (2006.01); G01N 33/50 (2006.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
C07D 407/04 (2013.01); A61K 45/06 (2013.01); C07D 213/38 (2013.01); C07D 307/52 (2013.01); C07D 333/20 (2013.01); G01N 33/502 (2013.01); G01N 21/64 (2013.01);
Abstract
In one aspect, the present disclosure provides compounds of the formula (I): In other aspects, the present disclosure provides compositions and methods of targeting GPER for the treatment of cancers, such as breast cancers and leukemias, gallstone disease, cardiovascular disease, and for conferring of neuroprotection on a subject. Also disclosed are high throughput assays for identifying antagonists of GPER.