The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 16, 2024

Filed:

Jun. 27, 2019
Applicants:

The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);

The U.s. Government Represented BY the Department of Veterans Affairs, NW Washington, DC (US);

Inventors:

David Myung, Stanford, CA (US);

Sarah Hull, Stanford, CA (US);

Sarah Heilshorn, Mountain View, CA (US);

Christopher Lindsay, San Mateo, CA (US);

Christopher Madl, Los Altos, CA (US);

Hyun Jong Lee, Gyeonggi-do, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61F 2/14 (2006.01); A61K 9/06 (2006.01); A61K 47/10 (2017.01); A61K 47/36 (2006.01); A61K 47/42 (2017.01);
U.S. Cl.
CPC ...
A61K 9/0051 (2013.01); A61F 2/142 (2013.01); A61K 9/06 (2013.01); A61K 47/10 (2013.01); A61K 47/36 (2013.01); A61K 47/42 (2013.01); A61F 2210/0076 (2013.01);
Abstract

Compositions and methods are provided for lamellar and defect reconstruction of corneal stromal tissue using biomaterials that form a defined gel structure in situ. Such gels can serve as cellular or acellular lamellar substitutes to reconstruct corneal stroma, facilitate matrix remodeling, and support multilayered re-epithelialization of wounded corneal stromal tissue, as well delivery vehicles for cells, biomolecules, and/or pharmaceutical agents to wound sites throughout the body.


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