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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12036272 B1

PDFFull Text
Date of Patent:
Jul. 16, 2024

Filed:

Dec. 09, 2022

Antigen presenting scaffolds for immune-cell manipulation

Applicant:

Danmarks Tekniske Universitet, Kgs. Lyngby, DK;

Inventors:

Sine Reker Hadrup, Virum, DK;

Vibeke Mindahl Rafa, Copenhagen S, DK;

Søren Nyboe Jakobsen, Charlottenlund, DK;

Assignee:

Danmarks Tekniske Universitet, Kgs. Lyngby, DK;

Attorney:

Knobbe, Martens, Olson & Bear, LLP

Primary Examiner:

Agnieszka Boesen

Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 35/17 (2015.01); A61K 39/12 (2006.01); A61K 39/145 (2006.01); A61K 39/245 (2006.01); A61P 31/16 (2006.01); A61P 31/22 (2006.01); A61P 35/00 (2006.01); C12M 1/12 (2006.01); C12N 5/00 (2006.01); C12N 5/0783 (2010.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); A61K 35/17 (2013.01); A61K 39/001104 (2018.08); A61K 39/001106 (2018.08); A61K 39/001112 (2018.08); A61K 39/001113 (2018.08); A61K 39/001114 (2018.08); A61K 39/001124 (2018.08); A61K 39/001168 (2018.08); A61K 39/001182 (2018.08); A61K 39/001195 (2018.08); A61K 39/12 (2013.01); A61K 39/145 (2013.01); A61K 39/245 (2013.01); A61P 31/16 (2018.01); A61P 31/22 (2018.01); A61P 35/00 (2018.01); C12M 25/14 (2013.01); C12N 5/0636 (2013.01); C12N 7/00 (2013.01); A61K 2039/5154 (2013.01); A61K 2039/5158 (2013.01); A61K 2039/55527 (2013.01); A61K 2039/55533 (2013.01); A61K 2039/605 (2013.01); A61K 2039/6087 (2013.01); A61K 2039/645 (2013.01); C12N 2501/2302 (2013.01); C12N 2501/2315 (2013.01); C12N 2501/2321 (2013.01); C12N 2501/50 (2013.01); C12N 2533/70 (2013.01); C12N 2710/16134 (2013.01); C12N 2710/16234 (2013.01); C12N 2760/16034 (2013.01);
Abstract

The present invention relates to artificial antigen presenting cell (aAPC) scaffolds to provide cells with specific functional stimulation to obtain phenotypic and functional properties ideal to mediate tumor regression or viral clearance. In particular, the scaffolds of the present invention comprise antigens, such as peptide-MHC (pMHC) class I molecules, and specific combinations of cytokines and co-stimulatory molecules to allow effective expansion and functional stimulation of specific T cells.

Find Patent Forward Citations

Hadrup, Sine. (2024). Antigen presenting scaffolds for immune-cell manipulation (U.S. Patent No. 12036272). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12036272

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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