The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2024
Filed:
Nov. 21, 2016
Universitat Autonoma DE Barcelona, Bellatera, ES;
Fundació Institució Català DE Recerca I Estudis Avançats, Barcelona, ES;
Miguel Chillon Rodriguez, Barcelona, ES;
Anna Masso Chacon, Vilanova i la Geltrú, ES;
Assumpció Bosch Merino, Sant Cugat del Vallès, ES;
Universitat Autònoma De Barcelona, Barcelona, ES;
Fundació Institució Català de Recerca i Estudis Avançats, Barcelona, ES;
Abstract
The invention discloses using secreted splicing variant of mammal Klotho (s-KL) as an agent for the prevention and/or treatment of cognitive and/or behaviour impairments. It also refers to gene constructs and expression vectors useful in gene therapy for the delivery of said s-KL variant to the central nervous system of a mammal, in particular a rodent or a human. Pharmaceutical compositions comprising either the protein s-KL or any gene construct for expressing the protein in the CNS are also disclosed.