The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 16, 2024

Filed:

Jul. 19, 2018
Applicants:

Fate Therapeutics, Inc., San Diego, CA (US);

Juno Therapeutics, Inc., Seattle, WA (US);

Inventors:

Jonathan Rosen, San Diego, CA (US);

Eigen Peralta, San Diego, CA (US);

Ian Hardy, San Diego, CA (US);

Betsy D. Rezner, San Diego, CA (US);

Christian Maine, San Diego, CA (US);

Daniel Shoemaker, San Diego, CA (US);

David Robbins, Temecula, CA (US);

Lucas Thompson, Seattle, WA (US);

Assignees:

FATE THERAPEUTICS, INC., San Diego, CA (US);

JUNO THERAPEUTICS, INC., Seattle, WA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C12N 5/0636 (2013.01); C12N 5/0646 (2013.01); C12N 2501/999 (2013.01); C12N 2506/02 (2013.01); C12N 2506/45 (2013.01); C12N 2510/00 (2013.01);
Abstract

Compounds that either produce a higher proportion or greater absolute number of phenotypically identified naive, stem cell memory, central memory T cells, adaptive NK cells, and type I NKT cells are identified. Compositions and methods for modulating immune cells including T, NK, and NKT cells for adoptive cell therapies, such as those providing improvements in one or more therapeutic outcomes, are provided.


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