The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2024
Filed:
Mar. 28, 2019
Applicant:
Università Degli Studi Di Bari Aldo Moro, Bari, IT;
Inventors:
Loreto Gesualdo, Altamura, IT;
Paola Pontrelli, Bari, IT;
Assignee:
UNIVERSITÀ DEGLI STUDI DI BARI ALDO MORO, Bari, IT;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/345 (2006.01); A61K 31/277 (2006.01); A61K 31/351 (2006.01); A61K 31/403 (2006.01); A61P 3/10 (2006.01); A61P 13/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/345 (2013.01); A61K 31/277 (2013.01); A61K 31/351 (2013.01); A61K 31/403 (2013.01); A61P 3/10 (2018.01); A61P 13/12 (2018.01);
Abstract
The present invention relates to a composition comprising at least one inhibitor of the enzymatic complex conjugating ubiquitin Ubc13/Uev1a and at least one anti-hypertensive agent inhibiting the renin-angiotensin-aldosterone system and/or a hypoglycemic agent. Medical uses and pharmaceutical compositions comprising this composition also fall within the scope of the present invention. In particular, this composition can be used for the treatment or prevention of the renal fibrotic damage, in particular in patients suffering from diabetes.