The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2024
Filed:
Sep. 18, 2020
Northwestern University, Evanston, IL (US);
Jiaxing Huang, Wilmette, IL (US);
SonBinh T. Nguyen, Evanston, IL (US);
Zhizhi Kong, Berkeley, CA (US);
Northwestern University, Evanston, IL (US);
Abstract
Methods of imaging a 2D sheet are provided. In embodiments, such a method comprises illuminating a sample with light having a wavelengththe sample comprising a quenching substrate; a transparent, non-quenching 2D sheet on the quenching substrate; and a fluorescent layer comprising fluorescent dye molecules on the transparent, non-quenching 2D sheet and the quenching substrate, providing background domains and 2D sheet domains in the sample, wherein the light induces fluorescence of the dye molecules in the fluorescent layer. The method further comprises detecting fluorescence from the sample to provide an image of the transparent, non-quenching 2D sheet, wherein an intensity Iof the detected fluorescence from the background domains is less than an intensity Is of the detected fluorescence from the 2D sheet domains, thereby providing contrast in the image.