The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2024
Filed:
Dec. 06, 2019
Flagship Pioneering Innovations Vi, Llc, Cambridge, MA (US);
Jacob Rosenblum Rubens, Cambridge, MA (US);
Geoffrey A. von Maltzahn, Somerville, MA (US);
Robert James Citorik, Somerville, MA (US);
Barrett Ethan Steinberg, Somerville, MA (US);
Donghui Li, Somerville, MA (US);
William Edward Salomon, West Roxbury, MA (US);
Flagship Pioneering Innovations VI, LLC, Cambridge, MA (US);
Abstract
Methods and compositions for modulating a target genome are disclosed. The composition may comprise a first RNA encoding a polypeptide comprising a retrotransposase reverse transcriptase domain and a retrotransposase endonuclease domain. The composition may also comprise a second RNA comprising a sequence that binds the polypeptide and a heterologous object sequence. The composition may insert the sequence of the heterologous object sequence into a target DNA.