The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 09, 2024

Filed:

Sep. 14, 2020
Applicant:

Becton Dickinson and Company, Franklin Lakes, NJ (US);

Inventors:

Patrick Shawn Beaty, Dallastown, PA (US);

Michael A. Brasch, Gaithersburg, MD (US);

Suneil Hosmane, Franklin Lakes, NJ (US);

David Polley, Cockeysville, MD (US);

Julie L Rosales, Randallstown, MD (US);

Kerry Lynn Smith, York, PA (US);

Assignee:

BECTON, DICKINSON AND COMPANY, Franklin Lakes, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/34 (2006.01); C12Q 1/02 (2006.01); C12Q 1/04 (2006.01); G01N 27/02 (2006.01); G01N 33/487 (2006.01); G01N 33/49 (2006.01);
U.S. Cl.
CPC ...
C12M 41/36 (2013.01); C12Q 1/02 (2013.01); C12Q 1/04 (2013.01); G01N 27/02 (2013.01); G01N 33/48785 (2013.01); G01N 27/026 (2013.01); G01N 33/49 (2013.01);
Abstract

A system and method with increased sensitivity to microorganism growth. The system includes signal processing electronic circuit connected to a consumable or vessel through two or more electrodes that fully penetrate the vessel and are in contact with the fluid contents. The electronic circuit is configured to detect a component of the total impedance of the sample, specifically the “out-of-phase” or imaginary reactance component, which has a sensitive response to organism growth in a frequency-dependent manner. The system detects changes in both the composition of charged molecules in the liquid matrix and the number of microorganisms based on monitoring the sample for change in this parameter. This results in a 5-70% reduction in time-to-detection (TTD). The system and method detect organisms in a plurality of vessel shapes, volumes, and matrix (or media) formats. The electrodes are fully immersed in a continuous body of liquid sample. The distance between electrodes may be adjusted or tuned to fit the needs of the vessel. The voltage inputs can also be adjusted to allow proper detection of the contents within the vessel.


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