The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2024
Filed:
Jul. 19, 2019
Applicant:
Oncohost Ltd., Binyamina, IL;
Inventor:
Morris C. Laster, Jerusalem, IL;
Assignee:
OncoHost Ltd., Binyamina, IL;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/15 (2015.01); A61P 35/00 (2006.01); C07K 14/54 (2006.01); C07K 14/705 (2006.01); C07K 14/725 (2006.01); C07K 14/735 (2006.01); C07K 16/28 (2006.01); C07K 16/32 (2006.01); C12N 5/0786 (2010.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/54 (2013.01); A61K 35/15 (2013.01); A61P 35/00 (2018.01); C07K 14/7051 (2013.01); C07K 14/70517 (2013.01); C07K 14/70521 (2013.01); C07K 14/70535 (2013.01); C07K 14/7056 (2013.01); C07K 16/2803 (2013.01); C07K 16/32 (2013.01); C12N 5/0645 (2013.01); A61K 38/00 (2013.01); C07K 2317/622 (2013.01); C07K 2319/03 (2013.01); C07K 2319/30 (2013.01); C07K 2319/33 (2013.01);
Abstract
The present invention provides macrophages genetically modified to express IL-31 or both IL-31 and a chimeric antigen receptor (CAR) for treatment of cancer. It further provides methods for treatment of cancer comprising administration of IL-31 along with genetically unmodified macrophages or genetically modified to express a CAR.