The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 09, 2024

Filed:

Aug. 15, 2022
Applicant:

Jiangnan University, Wuxi, CN;

Inventors:

Shenglong Zhu, Wuxi, CN;

Yongquan Chen, Wuxi, CN;

Zhen Wang, Wuxi, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/50 (2006.01); A61K 9/00 (2006.01); A61K 38/18 (2006.01); A61P 1/16 (2006.01); A61P 3/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/50 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 38/1825 (2013.01); A61P 1/16 (2018.01); A61P 3/00 (2018.01); A61P 35/00 (2018.01);
Abstract

The disclosure discloses an anti-metabolic disorder FGF analog and an application thereof, and belongs to the technical field of medicines. According to the disclosure, modification is performed based on an FGF19 mutant NGM282 to obtain a FGF19 analog, and the FGF19 analog is used in treating liver impairment, metabolic disorders, obesity, overweight, metabolic syndrome, diabetes and dyslipidemia and has no side effects of elevated cholesterol and dietary decline in a therapeutic process.


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