The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2024
Filed:
May. 30, 2019
Applicants:
University of Notre Dame Du Lac, South Bend, IN (US);
University of Kansas, Lawrence, KS (US);
Inventors:
Brian Blagg, Notre Dame, IN (US);
Sanket Mishra, Notre Dame, IN (US);
Assignees:
University of Notre Dame du Lac, South Bend, IN (US);
University of Kansas, Lawrence, KS (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61P 35/00 (2006.01); C07D 401/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61P 35/00 (2018.01); C07D 401/04 (2013.01);
Abstract
Described are compounds of formula (I), based on an isoquinolin-1(2H)-one backbone, that function as Hsp90β selective inhibitors. Also described are pharmaceutical compositions thereof and methods of treating cancer by administering compounds of formula (I).