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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12030857 B1

PDFFull Text
Date of Patent:
Jul. 09, 2024

Filed:

Jun. 25, 2019

Glucose uptake inhibitors

Applicant:

Kadmon Corporation, Llc, Bridgewater, NJ (US);

Inventors:

Kevin G. Liu, West Windsor, NJ (US);

Kellen L. Olszewski, Brooklyn, NY (US);

Ji-In Kim, Princeton, NJ (US);

Masha V. Poyurovsky, New York, NY (US);

Koi Morris, Plainsboro, NJ (US);

Xuemei Yu, Livingston, NJ (US);

Christophe Lamarque, Princeton, NJ (US);

Assignee:

Kadmon Corporation, LLC, Bridgewater, NJ (US);

Attorney:

McNeill Baur PLLC

Primary Examiner:

Deepak R Rao

Int. Cl.
CPC ...
C07D 239/42 (2006.01); C07D 239/94 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 403/12 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 417/12 (2006.01); C07D 471/04 (2006.01); C07D 473/34 (2006.01); C07D 491/048 (2006.01); C07D 491/052 (2006.01); C07D 495/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 239/42 (2013.01); C07D 239/94 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01); C07D 473/34 (2013.01); C07D 491/048 (2013.01); C07D 491/052 (2013.01); C07D 495/04 (2013.01); C07D 519/00 (2013.01);
Abstract

This invention provides compounds that modulate glucose uptake activity and cellular transport/uptake of glucose, and particularly GLUTS3, but also including but not limited to GLUT1-14 (SLC2A1-SLC2A14). Compounds of the invention are useful for treating diseases, including cancer, autoimmune diseases and inflammation, infectious diseases, and metabolic diseases.

Find Patent Forward Citations

Quick Actions:

Liu, Kevin. (2024). Glucose uptake inhibitors (U.S. Patent No. 12030857). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12030857

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