The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12030048 B1

Date of Patent:

Jul. 09, 2024

Filed:

Mar. 06, 2019

Microfluidic chip

Applicant:

Shenzhen Biorain Technology Co., Ltd., Guangdong, CN;

Inventors:

Linfen Yu, Guangdong, CN;

Wei Yang, Guangdong, CN;

Assignee:

SHENZHEN BIORAIN TECHNOLOGY CO., LTD., Shenzhen, CN;

Attorney:

Primary Examiner:

Jennifer Wecker

Assistant Examiner:

Oyeleye Alexander Alabi

Int. Cl.

CPC ...

B01L 3/00 (2006.01); B01F 23/00 (2022.01); B01F 23/41 (2022.01); B01F 101/23 (2022.01); B23Q 17/24 (2006.01); C12M 1/34 (2006.01); C12Q 1/04 (2006.01); C12Q 1/18 (2006.01); C12Q 1/686 (2018.01); G01N 21/3577 (2014.01); G01N 21/359 (2014.01); G01N 21/39 (2006.01); G01N 21/45 (2006.01); G01N 21/64 (2006.01); G01N 30/12 (2006.01); G01N 30/68 (2006.01); G01N 30/70 (2006.01); G01N 30/72 (2006.01); G01N 30/88 (2006.01); G01N 33/00 (2006.01); G01N 33/18 (2006.01); G01N 33/50 (2006.01); G01N 33/68 (2006.01);

U.S. Cl.

CPC ...

B01L 3/50273 (2013.01); B01L 3/502715 (2013.01); B01L 3/502753 (2013.01); B01L 3/502784 (2013.01); B01L 2200/0684 (2013.01); B01L 2200/0689 (2013.01); B01L 2300/04 (2013.01); B01L 2300/0627 (2013.01); B01L 2300/0681 (2013.01); C12Q 1/686 (2013.01);

Abstract

Disclosed is a microfluidic chip, including a chip upper cover, a chip lower layer, a membrane, a sealing gasket and a sealing ring. The microfluidic chip is provided with a sample storage zone, a droplet formation zone, a droplet storage zone, a droplet detection zone and a waste liquid storage zone. The sample storage zone, the droplet formation zone, the droplet storage zone, the droplet detection zone and the waste liquid storage zone communicate by means of a micropore or a micro-channel. The droplet formation zone is used to transform the sample phase into tens of thousands to millions of droplets, the droplets undergo the PCR reaction in the droplet storage zone, the droplet detection zone is used to perform optical detection on the droplets after PCR reaction, and the waste liquid storage zone is used to collect and store the detected droplets and continuous phase.

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