The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2024
Filed:
May. 11, 2020
Applicant:
Yale University, New Haven, CT (US);
Inventor:
Aaron Ring, New Haven, CT (US);
Assignee:
Yale University, New Haven, CT (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/48 (2006.01); A61K 38/16 (2006.01); A61P 35/00 (2006.01); C07K 14/54 (2006.01); G06G 7/48 (2006.01); G06G 7/58 (2006.01);
U.S. Cl.
CPC ...
A61K 38/16 (2013.01); A61P 35/00 (2018.01); C07K 14/54 (2013.01); G06G 7/48 (2013.01); G06G 7/58 (2013.01);
Abstract
The present disclosure provides methods of making and methods of using IL-18 mimic polypeptides for use in therapeutic and non-therapeutic applications. The synthetic IL-18 mimics an increase IL-18R signaling activity even in the presence of an inhibitory molecule such as IL-18BP.