The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 09, 2024

Filed:

Apr. 10, 2020
Applicant:

Riboscience Llc, Palo Alto, CA (US);

Inventors:

Ronald Hawley, Palo Alto, CA (US);

Klaus Klumpp, Palo Alto, CA (US);

Assignee:

Riboscience LLC, Palo Alto, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07F 5/02 (2006.01); A61K 31/675 (2006.01); A61K 31/683 (2006.01); A61K 31/69 (2006.01); A61K 45/06 (2006.01); C07F 9/6503 (2006.01); C07F 9/6506 (2006.01);
U.S. Cl.
CPC ...
A61K 31/69 (2013.01); A61K 31/675 (2013.01); A61K 31/683 (2013.01); A61K 45/06 (2013.01); C07F 5/027 (2013.01); C07F 9/65038 (2013.01); C07F 9/65068 (2013.01);
Abstract

The present disclosure provides certain bicyclic heteroaryl compounds that inhibit ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) enzymatic activity and are therefore useful for the treatment of diseases and conditions modulated at least in part by ENPP1. In some embodiments, the bicyclic heteroaryl compounds includes those of Formula (I). Also provided herein are pharmaceutical compositions containing such compounds and processes for preparing such compounds.


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