The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 02, 2024

Filed:

Apr. 19, 2021
Applicant:

Quest Diagnostics Investments Llc, Secaucus, NJ (US);

Inventors:

Dov Shiffman, Palo Alto, CA (US);

Carmen Tong, Dublin, CA (US);

James J. Devlin, Lafayette, CA (US);

Michael J. McPhaul, Capistrano Beach, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/49 (2006.01); G01N 30/72 (2006.01); G01N 33/68 (2006.01); G01N 33/74 (2006.01);
U.S. Cl.
CPC ...
G01N 33/492 (2013.01); G01N 30/7266 (2013.01); G01N 33/6848 (2013.01); G01N 33/74 (2013.01); G01N 2333/62 (2013.01); G01N 2800/042 (2013.01); G01N 2800/50 (2013.01);
Abstract

Methods are described for diagnosing or prognosing insulin resistance in diabetic and pre-diabetic patients, the method comprising determining the amount of insulin and C-peptide in a sample. Provided herein are mass spectrometric methods for detecting and quantifying insulin and C-peptide in a biological sample utilizing enrichment and/or purification methods coupled with tandem mass spectrometric or high resolution/high accuracy mass spectrometric techniques.


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