The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 2024
Filed:
Aug. 06, 2021
Bio-rad Laboratories, Inc., Hercules, CA (US);
John F. Regan, San Mateo, CA (US);
Dianna Maar, Mountain House, CA (US);
Dawne N. Shelton, San Ramon, CA (US);
Tina C. Legler, Tracy, CA (US);
Samantha Cooper, Berkeley, CA (US);
Wei Yang, Dublin, CA (US);
Eli A. Hefner, Fairfield, CA (US);
Niels Klitgord, Oakland, CA (US);
Bio-Rad Laboratories, Inc., Hercules, CA (US);
Abstract
Method of analysis for alleles of a target. In the method, a plurality of fluid volumes may be formed. Each fluid volume may contain a first primer pair to amplify a first allele of a target, a second primer pair to amplify a second allele of the target, a first reporter including a first photoluminophore and providing a primer of the first primer pair, and a second reporter including a second photoluminophore and providing a primer of the second primer pair. Each of the first and second reporters may include an oligomer having a quencher, and the oligomer may be configured to base-pair with the primer of the first primer pair and the primer of the second primer pair. The first and second alleles may be amplified using the first and second primer pairs. Photoluminescence may be detected. A level of each allele may be determined.