The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 2024
Filed:
Aug. 18, 2021
Nanjing Tech University, Nanjing, CN;
Chenjie Zhu, Nanjing, CN;
Hanjie Ying, Nanjing, CN;
Zhuotao Tan, Nanjing, CN;
Wei Zhuang, Nanjing, CN;
Yaping Fu, Nanjing, CN;
Yaoying Han, Nanjing, CN;
Ming Li, Nanjing, CN;
Yong Chen, Nanjing, CN;
Dong Liu, Nanjing, CN;
Huanqing Niu, Nanjing, CN;
Pengpeng Yang, Nanjing, CN;
NANJING TECH UNIVERSITY, Nanjing, CN;
Abstract
A method for preparing a nitrogen-containing heterocyclic compound and a derivative thereof by an enzymatic-chemical cascade method, comprising: reacting an alcohol, an amine, an alcohol dehydrogenase, a flavin molecule and a coenzyme in a solvent to obtain the nitrogen-containing heterocyclic compound and the derivative thereof; compared with the prior art, the method is a green and economical enzymatic-chemical cascade method, and is used for synthesizing nitrogen-containing heterocyclic compounds and derivatives thereof; compared with a common toxic chemical catalyst, the alcohol dehydrogenase is selected as a catalyst in the method, which has the characteristics of high substrate specificity, no pollution, high catalytic efficiency, no toxic solvents and simple post-treatment.