The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 02, 2024

Filed:

Sep. 07, 2018
Applicant:

Genesis Technologies Limited, St. Michael, BB;

Inventors:

Jan-Eric Ahlfors, Laval, CA;

Rouwayda El-Ayoubi, Laval, CA;

Assignee:

Genesis Technologies Limited, St. Michael, BB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/071 (2010.01); C12N 5/074 (2010.01); C12N 5/0775 (2010.01); C12N 5/0789 (2010.01); C12N 5/0797 (2010.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0696 (2013.01); C12N 5/0623 (2013.01); C12N 5/0647 (2013.01); C12N 5/0662 (2013.01); C12N 5/0678 (2013.01); C12N 15/85 (2013.01); C12N 2501/40 (2013.01); C12N 2501/60 (2013.01); C12N 2501/603 (2013.01); C12N 2501/604 (2013.01); C12N 2501/605 (2013.01); C12N 2501/998 (2013.01); C12N 2502/99 (2013.01); C12N 2506/094 (2013.01); C12N 2506/11 (2013.01); C12N 2506/1307 (2013.01); C12N 2506/1384 (2013.01);
Abstract

Described herein are reprogrammed cells, and methods for cell dedifferentiation, transformation and eukaryotic cell reprogramming. Also described are cells, cell lines, and tissues that can be transplanted in a patient after steps of in vitro dedifferentiation and in vitro reprogramming. In particular embodiments the cells are Stem-Like Cells (SLCs), including Neural Stem-Like Cells (NSLCs), Cardiac Stem-Like Cells (CSLC), Hematopoietic Stem-Like Cells (HSLC), Pancreatic Progenitor-Like Cells, and Mesendoderm-like Cells. Also described are methods for generating these cells from human somatic cells and other types of cells. Also provided are compositions and methods of using of the cells so generated in human therapy and in other areas.


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