The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 02, 2024

Filed:

Aug. 07, 2020
Applicant:

University of Massachusetts, Boston, MA (US);

Inventors:

Anastasia Khvorova, Westborough, MA (US);

Julia Alterman, Worcester, MA (US);

Faith Conroy, Worcester, MA (US);

Edith Pfister, Boxborough, MA (US);

Neil Aronin, Newtonville, MA (US);

Ken Yamada, Boston, MA (US);

Assignee:

UNIVERSITY OF MASSACHUSETTS, Boston, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12N 2310/14 (2013.01); C12N 2310/52 (2013.01);
Abstract

Novel oligonucleotides that enhance silencing of the expression of a gene containing a single nucleotide polymorphism (SNP) relative to the expression of the corresponding wild-type gene are provided. Methods of using novel oligonucleotides that enhance silencing of the expression of a gene containing a SNP relative to the expression of the corresponding wild-type gene are provided.


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