The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 02, 2024

Filed:

Nov. 05, 2021
Applicant:

Cytequest, Inc., Ithaca, NY (US);

Inventors:

Thomas N. Corso, Groton, NY (US);

Harold G. Craighead, Ithaca, NY (US);

Assignee:

CyteQuest, Inc., Ithaca, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/42 (2006.01); C12M 1/02 (2006.01); C12M 1/34 (2006.01); C12N 13/00 (2006.01); C12N 15/87 (2006.01);
U.S. Cl.
CPC ...
C12M 35/02 (2013.01); C12M 27/00 (2013.01); C12M 41/46 (2013.01); C12N 13/00 (2013.01); C12N 15/87 (2013.01);
Abstract

A system, device and method for electroporation of living cells and the introduction of selected molecules into the cells utilizes a fluidic system where living cells and biologically active molecules flow through a channel that exposes them to electric fields, causing the molecules to be transferred across the cell membrane. The device is structured in a manner that allows precise control of the cells location, motion, and exposure to electric fields within the flow channel device. The method is particularly well suited for the introduction of DNA, RNA, drug compounds, and other biologically active molecules into living cells.


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