The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 2024
Filed:
Oct. 22, 2021
Asher Biotherapeutics, Inc., South San Francisco, CA (US);
Yik Andy Yeung, South San Francisco, CA (US);
Ivana Djuretic, Pacifica, CA (US);
Paul Bessette, San Francisco, CA (US);
Wei Chen, Cupertino, CA (US);
Sherman Michael Chin, Burlingame, CA (US);
Kelly Dare Moynihan, San Francisco, CA (US);
Henry C. Nguyen, San Francisco, CA (US);
Irene Ni, Foster City, CA (US);
Danielle C. Pappas, San Mateo, CA (US);
Terrence Park, Hayward, CA (US);
Asher Biotherapeutics, Inc., South San Francisco, CA (US);
Abstract
Provided herein are anti-CD8 antigen binding molecules and fusion polypeptides comprising the CD8 antigen binding molecules for selectively modulating the function of CD8+ T cells over other immune cells. In addition, the present disclosure also provides polynucleotides encoding the disclosed antigen binding molecules and fusion polypeptides, and vectors and host cells comprising such polynucleotides. The present disclosure further provides methods for producing the antigen binding molecules and fusion polypeptides, pharmaceutical compositions comprising the same, and uses thereof.