The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 02, 2024

Filed:

Jul. 01, 2021
Applicant:

Incyte Corporation, Wilmington, DE (US);

Inventors:

Lei Qiao, Downingtown, PA (US);

Lingkai Weng, Phoenixville, PA (US);

Chongsheng Eric Shi, Wilmington, DE (US);

David Meloni, Bear, DE (US);

Qiyan Lin, Newark, DE (US);

Michael Xia, Wilmington, DE (US);

Vaqar Sharief, Newark, DE (US);

William Frietze, Kennett Square, PA (US);

Zhongjiang Jia, Kennett Square, PA (US);

Yongchun Pan, Newark, DE (US);

Pingli Liu, Newark, DE (US);

Tai-Yuen Yue, Hockessin, DE (US);

Jiacheng Zhou, Newark, DE (US);

Jianji Wang, New Castle, DE (US);

Assignees:

Incyte Corporation, Wilmington, DE (US);

Incyte Holdings Corporation, Wilmington, DE (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present application provides processes for preparing (R)-4-(3-((S)-1-(4-amino-3-methyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-5-chloro-2-ethoxy-6-fluorophenyl)pyrrolidin-2-one, which is useful as an inhibitor phosphoinositide 3-kinase-delta (PI3Kδ), as well as a salt form and intermediates related thereto.


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