The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 2024
Filed:
Nov. 28, 2019
Commissariat a L'energie Atomique ET Aux Energies Alternatives, Paris, FR;
Jean-Christophe Cintrat, Igny, FR;
Julien Barbier, Gif-sur-Yvette, FR;
Daniel Gillet, Antony, FR;
Alain Pruvost, Choisel, FR;
Audrey Couhert, Villefontaine, FR;
Livia Tepshi, Antony, FR;
Robin Vinck, Gif-sur-Yvette, FR;
Abstract
The invention relates to a new family of compounds of the type 2,3-dihydroquinazolin-4(1H)-one and the use thereof as inhibitors of the toxic effects of intracellular-acting toxins, such as ricin, Shiga toxins or the cholera toxin, using retrograde transport to intoxicate the cells, or viruses or bacteria using retrograde and/or syntaxin 5-dependent transport to infect the cells, specifically viruses or bacteria entering into the cells by means of endocytosis, or intracellular parasites.