The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 2024
Filed:
Mar. 19, 2018
Applicant:
Merck Patent Gmbh, Darmstadt, DE;
Inventors:
Rudolf Moser, Schaffhausen, CH;
Viola Groehn, Dachsen, CH;
Cristina Mueller, Nussbaumen, CH;
Roger Schibli, Baden, CH;
Simon Ametamey, Zurich, CH;
Silvan Boss, Port, CH;
Assignee:
Merck Patent GmbH, Darmstadt, DE;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/04 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 51/0459 (2013.01); A61K 45/06 (2013.01);
Abstract
The present invention is directed towards isomerically pureF-labelled (6S)- or (6R)-5-methyltetrahydrofolate radiopharmaceuticals, wherein the phenyl group within the folate structure, has been replaced by anF-labelled N-heterocycle, for use in diagnostic imaging of a cell or population of cells expressing a folate-receptor in vitro or in vivo or for use in monitoring of cancer or inflammatory and autoimmune diseases and therapy thereof.