The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 02, 2024

Filed:

May. 10, 2019
Applicant:

National Centre for Cell Science, Maharashtra, IN;

Inventors:

Debashis Mitra, Maharashtra, IN;

Jay Trivedi, Maharashtra, IN;

Assignee:

NATIONAL CENTRE FOR CELL SCIENCE, Pune Maharashtra, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 45/06 (2006.01); A61P 31/18 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 45/06 (2013.01); A61P 31/18 (2018.01);
Abstract

The present invention relates to compounds and pharmaceutical composition having antiviral effects. Over 1200 molecules were screened and 55 molecules having statistically significant anti-HIV activity were identified and selected. The compound Methotrexate (MTX-HYD) and its analogues, the combinations thereof and their combination with other anti-retrovirals were selected for repurposing the compounds as anti-HIV drugs. The present invention may further relate to pharmaceutical composition comprising compounds in combination with active drugs having anti-HIV activity.


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