The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 02, 2024

Filed:

Aug. 17, 2019
Applicants:

Ptc Therapeutics, Inc., South Plainfield, NJ (US);

The Trustees of Columbia University IN the City of New York, New York, NY (US);

Inventors:

Marla L. Weetall, Morristown, NJ (US);

Liangxian Cao, East Brunswick, NJ (US);

Thomas W. Davis, South Orange, NJ (US);

Melissa L. Dumble, Watchung, NJ (US);

Jaime A. Eberle-Singh, Philadelphia, PA (US);

Kenneth P. Olive, New York, NY (US);

Assignee:

PTC THERAPEUTICS, INC., Warren, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); A61K 31/337 (2006.01); A61K 31/7068 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); A61K 31/337 (2013.01); A61K 31/7068 (2013.01); A61P 35/00 (2018.01);
Abstract

A method for treating pancreatic cancer in a subject in need thereof comprising, administering to the subject an effective amount of a tubulin polymerization inhibitor compound is described herein. More particularly, a method for treating pancreatic ductal adenocarcinoma in a subject in need thereof comprising, administering to the subject an effective amount of a substituted reverse pyrimidine tubulin polymerization inhibitor compound alone or in combination with other chemo-therapeutic agents is described herein.


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