The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2024

Filed:

Jun. 04, 2021
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Farzad Fereidouni, Sacramento, CA (US);

Richard M. Levenson, Davis, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G02B 27/28 (2006.01); A61B 5/00 (2006.01); G01N 21/27 (2006.01); G01N 21/47 (2006.01); G01N 21/64 (2006.01); G02B 21/00 (2006.01); G02B 21/08 (2006.01); G02B 21/16 (2006.01); G06T 7/00 (2017.01);
U.S. Cl.
CPC ...
G02B 27/283 (2013.01); A61B 5/0071 (2013.01); G01N 21/27 (2013.01); G01N 21/47 (2013.01); G01N 21/6486 (2013.01); G02B 21/082 (2013.01); G02B 21/16 (2013.01); G06T 7/0012 (2013.01); G01N 21/6458 (2013.01); G02B 21/0092 (2013.01); G06T 2207/30024 (2013.01); G06T 2207/30096 (2013.01);
Abstract

The system includes: a sample holder configured to hold a stained tissue sample; an objective positioned to gather and focus light from the stained tissue sample; and a white light source that produces unpolarized white light and a polarizing beam splitter that allows one polarization direction of the white light to pass through to form an illumination beam having a first polarization direction, which is directed through the objective and onto the stained tissue sample causing the stained tissue sample to remit light that passes back through the objective and into the polarizing beam splitter. The polarizing beam splitter divides the remitted light into two orthogonally polarized remitted light beams, wherein one of the beams provides an imaging beam, which has a second polarization direction that is substantially orthogonal to the first polarization direction. Finally, the system includes an imaging device, which captures the imaging beam.


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