The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2024
Filed:
Aug. 17, 2017
Applicant:
Quest Diagnostics Investments Llc, Secaucus, NJ (US);
Inventors:
Michael J. McPhaul, San Juan Capistrano, CA (US);
Heather R. Sanders, Winchester, CA (US);
Assignee:
Quest Diagnostics Investments LLC, Secaucus, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C40B 30/04 (2006.01); A61K 31/03 (2006.01); A61K 31/48 (2006.01); A61K 31/567 (2006.01); A61K 31/4174 (2006.01); A61K 31/4439 (2006.01); A61K 31/444 (2006.01); A61K 31/451 (2006.01); A61K 31/496 (2006.01); A61K 31/506 (2006.01); C12Q 1/6806 (2018.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
C40B 30/04 (2013.01); A61K 31/03 (2013.01); A61K 31/48 (2013.01); A61K 31/567 (2013.01); A61K 31/4174 (2013.01); A61K 31/4439 (2013.01); A61K 31/444 (2013.01); A61K 31/451 (2013.01); A61K 31/496 (2013.01); A61K 31/506 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6886 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/156 (2013.01);
Abstract
The present technology is related to methods for detecting genetic alterations underlying intracranial neoplasms such as pituitary adenomas, meningiomas, and craniopharyngiomas. The methods disclosed herein are useful in determining whether a patient harboring an intracranial tumor will benefit from or is predicted to be responsive to treatment with an individual therapeutic agent or a specific combination of therapeutic agents. Kits for use in practicing the methods are also provided.