The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2024
Filed:
Aug. 25, 2021
Exosome Diagnostics, Inc., Waltham, MA (US);
Mikkel Noerholm, Gauting, DE;
Susan Belzer, St. Louis Park, MN (US);
Charlotte Romain, St. Louis Park, MN (US);
Johan Karl Olov Skog, Charlestown, MA (US);
Leileata M. Russo, New York, NY (US);
Wayne Comper, New York, NY (US);
Exosome Diagnostics, Inc., Waltham, MA (US);
Abstract
The present invention features a method and kit for isolating microvesicles or extracting microvesicle nucleic acids from a biological sample by using a control particle. The present invention provides control particles that are viruses or virus-like particles, such as bacteriophages, that contain control nucleic acids that can be detected to assess the accuracy, reliability, and efficiency of the microvesicle isolation or nucleic acid extraction steps. The methods described herein may further comprise the analysis of the presence, absence, or level of at least one biomarker associated with a disease or medical condition for diagnosing, prognosing, or monitoring the disease or medical condition.