The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2024

Filed:

May. 29, 2020
Applicants:

Massachusetts Institute of Technology, Cambridge, MA (US);

Imperial College Innovations Limited, London, GB;

Inventors:

Darrell J. Irvine, Arlington, MA (US);

Jason Y. H. Chang, Cambridge, MA (US);

Sylvain Ladame, Tring, GB;

Dana Al Sulaiman, London, GB;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6806 (2018.01); C12M 1/34 (2006.01); C12Q 1/6823 (2018.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6806 (2013.01); C12M 41/36 (2013.01); C12Q 1/6823 (2013.01); G01N 21/6428 (2013.01); C12Q 2565/1025 (2013.01); C12Q 2565/629 (2013.01);
Abstract

The present disclosure relates to a device, comprising a base and a plurality of microneedles attached to the base, wherein each microneedle has an outer surface; the outer surface of at least one microneedle being coated with a composition comprising at least one polymer and least one Peptide Nucleic Acid (PNA). The present disclosure additionally relates to a method of detecting an analyte in interstitial fluid (ISF), comprising contacting the device to a subject, for example, to human skin.


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