The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2024
Filed:
May. 21, 2019
Applicant:
Dsm Ip Assets B.v., Heerlen, NL;
Inventors:
Christopher Mark Farrell, Columbia, MD (US);
Lisa Ann Laprade, Columbia, MD (US);
Otto Martin Lehmann, Kaiseraugst, CH;
Joshua Trueheart, Columbia, MD (US);
Bastien Jean Wolfgang Chevreux, Kaiseraugst, CH;
Assignee:
DSM IP Assets B.V., Heerlen, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 33/02 (2006.01); C12N 1/16 (2006.01); C12N 9/02 (2006.01); C12R 1/645 (2006.01);
U.S. Cl.
CPC ...
C12P 33/02 (2013.01); C12N 1/165 (2021.05); C12N 9/0071 (2013.01); C12R 2001/645 (2021.05);
Abstract
The present invention is related to an improved method for production of 7-dehydrocholesterol (7-DHC), an important intermediate towards biotechnological production of vitamin D3 or derivatives/metabolites thereof. The invention features modified host strains expressing enzymes having improved C-5 sterol 5 desaturase activity and their use in a process for production of vitamin D3 or derivatives and/or metabolites thereof.