The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2024
Filed:
Nov. 13, 2020
Janssen Biotech, Inc., Horsham, PA (US);
Ricardo Attar, Lawrenceville, NJ (US);
Jason Dehart, San Diego, CA (US);
Selina Khan, Leiden, NL;
Vinod Krishna, Philadelphia, PA (US);
Jenifer Lum, Castro Valley, CA (US);
Christian Maine, San Diego, CA (US);
Barbara Sanders, Amsterdam, NL;
Manuel Alejandro Sepulveda, West Windsor, NJ (US);
Patrick Wilkinson, Collegeville, PA (US);
Roland Zahn, Rijnsburg, NL;
Janssen Biotech, Inc., Horsham, PA (US);
Abstract
Provided are vaccines, polypeptides and polynucleotides based on mutant CALR and JAK2 sequences, vectors, host cells, viruses, and methods of making and using them. The disclosure also provides methods of inducing an immune response and methods of treating, preventing, reducing a risk of onset or delaying the onset of a clinical condition characterized by an expression of JAK2V617F or CALR exon 9 mutant, or both JAK2V617F and CALR exon 9 mutant, wherein the method comprises a plurality of administrations of any of the compositions comprising polynucleotides, polypeptides or vectors disclosed herein.