The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2024
Filed:
Sep. 02, 2021
Miltenyi Biotec B.v. & Co. KG, Bergisch Gladbach, DE;
Thomas Schaser, Bergisch Gladbach, DE;
Andrew Kaiser, Bergisch Gladbach, DE;
Laura Kapitza, Bergisch Gladbach, DE;
Jessica Hartmann, Bergisch Gladbach, DE;
Frederic Thalheimer, Bergisch Gladbach, DE;
Christian Buchholz, Bergisch Gladbach, DE;
Miltenyi Biorec B V. Co., KG, Bergisch Gladbach, DE;
Abstract
The present invention provides a composition comprising i) a pseudotyped retroviral vector particle comprising a) one envelope protein with antigen-binding activity, wherein said envelope protein is a recombinant protein that does not interact with at least one of its original receptors and is fused at its ectodomain to a polypeptide comprising an antigen binding domain specific for CD62L, and wherein said envelope protein is protein G, HN or H derived from the Paramyxoviridae family, b) one envelope protein with fusion activity derived from the Paramyxoviridae family, and T cells expressing CD62L. Alternatively, when said polypeptide comprising an antigen binding domain is specific for a tag of a tagged polypeptide instead of the antigen binding domain specific for CD62L, wherein said tagged polypeptide binds specifically to CD62L, then the composition comprises further said tagged polypeptide.