The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2024

Filed:

Sep. 20, 2018
Applicant:

Council of Scientific & Industrial Research, New Delhi, IN;

Inventors:

Deepak Kumar Sharma, Chandigarh, IN;

Arpit Gupta, Chandigarh, IN;

Gajendra Pal Singh Raghava, New Delhi, IN;

Gautam Ankur, Chandigarh, IN;

Manisha Kumari, Chandigarh, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); A61K 38/00 (2006.01); C12N 15/10 (2006.01); C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); C12N 15/1055 (2013.01); C12P 21/02 (2013.01); A61K 38/00 (2013.01);
Abstract

The present disclosure provides a novel peptide as potent inhibitor of protein aggregation. A peptide for an inhibition of protein aggregation having the general Formula 1, [XSACX]HHHH[XXCGG](SEQ ID NO. 9) is provided. The m is 0 or 1; Xis an acetyl group; Xis a hydrophilic polar uncharged amide group containing amino acid; Xis His or Leu; and Xis His or Ser. The present disclosure specifically relates to peptide-based inhibitors useful in treatment of amyloid related disorders.


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