The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2024
Filed:
Dec. 11, 2020
University Medical Center Hamburg-eppendorf, Hamburg, DE;
Friedrich Nolte, Hamburg, DE;
Peter Bannas, Hamburg, DE;
Kerstin Schütze, Hamburg, DE;
William Fumey, Hamburg, DE;
Levin Schriewer, Hamburg, DE;
Stephan Menzel, Hamburg, DE;
Catelijne Stortelers, Ghent, BE;
University Medical Center Hamburg-Eppendorf, Hamburg, DE;
Abstract
The invention relates to polypeptides specifically binding to CD38 and are therefore suitable for the diagnosis and for the therapeutic and prophylactic treatment of diseases which are characterized by increased CD38 expression. Conjugates and pharmaceutical compositions comprising the polypeptides are disclosed as well. In addition, the invention relates to the use of such polypeptides in methods for the detection of CD38 and/or CD38-expressing cells in a biological sample. A process for the purification and concentration of CD38 and/or CD38-expressing cells in which the antigen-binding polypeptides are used are also described.