The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2024

Filed:

Aug. 09, 2021
Applicants:

Medimmune, Llc, Gaithersburg, MD (US);

Humabs Biomed SA, Bellinzona, CH;

Inventors:

Qun Wang, Gaithersburg, MD (US);

Charles K. Stover, Gaithersburg, MD (US);

Meghan Pennini, Gaithersburg, MD (US);

Chew-shun Chang, Gaithersburg, MD (US);

Xiaodong Xiao, Gaithersburg, MD (US);

Jamese Hilliard, Gaithersburg, MD (US);

Gilad Kaplan, Gaithersburg, MD (US);

Davide Corti, Bellinzona, CH;

Elisabetta Cameroni, Bellinzona, CH;

Martina Beltramello, Bellinzona, CH;

Assignees:

MedImmune, LLC, Gaithersburg, MD (US);

Humabs BioMed SA, Bellinzona, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/12 (2006.01); A61K 31/407 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01); A61P 31/04 (2006.01); C12N 15/63 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1228 (2013.01); A61P 31/04 (2018.01); C12N 15/63 (2013.01); A61K 31/407 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/565 (2013.01); C07K 2317/734 (2013.01); C07K 2317/76 (2013.01);
Abstract

The present disclosure provides binding proteins (e.g., antibodies or antigen binding fragments thereof) that specifically bind toO1 and induce opsonophagocytic killing of(e.g.,). The present disclosure also provides methods of reducing(e.g.,) or treating or preventing(e.g.,) infection in a subject comprising administering theO1 binding proteins, (e.g., antibodies or antigen-binding fragments thereof) to the subject.


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