The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2024
Filed:
Jan. 31, 2023
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);
Peter Collins, Silver Spring, MD (US);
Bo Liang, Boyds, MD (US);
Shirin Munir, Potomac, MD (US);
Anne Schaap Nutt, Austin, TX (US);
Ursula Buchholz, Silver Spring, MD (US);
Natalie Mackow, East Setauket, NY (US);
Peter Kwong, Washington, DC (US);
Barney Graham, Smyrna, GA (US);
Jason McLellan, Austin, TX (US);
Abstract
Recombinant paramyxoviruses including a viral genome encoding a heterologous gene are provided. In several embodiments, the recombinant paramyxovirus is a recombinant parainfluenza virus, such as a recombinant PIV3 including a viral genome encoding a heterologous respiratory syncytial virus F ectodomain linked to the transmembrane domain and the cytoplasmic tail of the F protein from the PIV3. Nucleic acid molecules including the genome of a recombinant paramyxoviruses are also provided. The recombinant viruses may advantageously be used in vaccine formulations, such as for vaccines against parainfluenza virus and respiratory syncytial virus.