The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2024

Filed:

Jun. 05, 2019
Applicant:

The Institute of Cancer Research: Royal Cancer Hospital, London, GB;

Inventors:

Leo Leung, Macclesfield, GB;

Kiri North, Abingdon, GB;

Deborah Smithen, Macclesfield, GB;

Mohammed Aljarah, Macclesfield, GB;

Michael Brown, Macclesfield, GB;

Ben Ayers, Singapore, SG;

Dan Niculescu-Duvaz, Macclesfield, GB;

Caroline Springer, Macclesfield, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61P 35/00 (2018.01);
Abstract

The disclosure relates to compounds of Formula (I), or pharmaceutically acceptable salts thereof, wherein Xand Xis each selected from CRor N; X, Xand Xis each selected from CR, CRor N, provided at least one of X, Xand Xis CRand provided only one of X, X, X, Xand Xcan be N. R, R, R, R, R, L, Land Lare as defined herein. Compounds according to Formula (I) are pharmacologically effective as lysyl oxidase (LOX) inhibitors and are believed to be useful in the treatment of, for instance, cancer.


Find Patent Forward Citations

Loading…