The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2024
Filed:
Apr. 15, 2020
Applicant:
China Resources Biopharmaceutical Company Limited, Beijing, CN;
Inventors:
Yaxian Cai, Shanghai, CN;
Xiaobing Yan, Shanghai, CN;
Ting Wang, Shanghai, CN;
Chengde Wu, Shanghai, CN;
Charles Z. Ding, Shanghai, CN;
Shuhui Chen, Shanghai, CN;
Assignee:
China Resources Biopharmaceutical Company Limited, Beijing, CN;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/18 (2006.01);
U.S. Cl.
CPC ...
C07D 471/18 (2013.01);
Abstract
Disclosed are a class of macrocyclic derivatives, a preparation method therefor, a pharmaceutical composition containing the derivatives, and the use thereof as therapeutic agents, particularly as XIa factor inhibitors and in the preparation of a drug for treating and preventing thromboembolisms and other diseases. Particularly disclosed are compounds shown by formula (I), an isomer thereof and a pharmaceutically acceptable salt thereof.