The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2024

Filed:

Nov. 19, 2021
Applicant:

Pliant Therapeutics, Inc., South San Francisco, CA (US);

Inventors:

Jacob Cha, San Bruno, CA (US);

Katerina Leftheris, San Mateo, CA (US);

Qi Gao, Franklin Park, NJ (US);

Jian Wang, Branchburg, NJ (US);

Dalian Zhao, Fanwood, NJ (US);

Assignee:

PLIANT THERAPEUTICS, INC., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07B 2200/13 (2013.01);
Abstract

Provided herein are integrin inhibitors, compositions thereof, and methods of their uses. Crystalline forms of salts of the inhibitors are also described, along with methods of preparing the crystalline forms. X-ray powder diffraction data, thermogravimetric analysis, and differential scanning calorimetry data are provided for the crystalline forms. The integrin inhibitors are useful for treatment of, inter alia, fibrotic diseases.


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