The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2024
Filed:
Jun. 21, 2021
The Research Foundation for the State University of New York, Albany, NY (US);
Iwao Ojima, Port Jefferson, NY (US);
Vincent Alford, Sunnyvale, CA (US);
Anushree Kamath, Issaquah, WA (US);
Jian Cao, S. Setauket, NY (US);
Xiadong Ren, Port Jefferson Station, NY (US);
Nicole Sampson, Setauket, NY (US);
Monaf Awwa, Bel Air, MD (US);
The Research Foundation for The State University of New York, Albany, NY (US);
Abstract
The invention relates to substituted pyrimidine compounds with the following formula: or a pharmaceutically acceptable salt, stereoisomer, or tautomer thereof. These compounds selectively target the hemopexin domain of matrix metalloproteinase 9 (MMP-9) and do not inhibit the protease's catalytic functions. The invention also relates to methods of treating cancer in a patient in need thereof with the compounds.