The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2024

Filed:

Dec. 12, 2019
Applicant:

Exelixis, Inc., Alameda, CA (US);

Inventors:

Frenel DeMorin, Long Beach, CA (US);

Khalid Shah, Half Moon Bay, CA (US);

Sagar Shakya, San Diego, CA (US);

Peter Wong, Brisbane, CA (US);

Courtney S. Johnson, West Lafayette, IN (US);

Melanie Janelle Bevill, West Lafayette, IN (US);

Stephan D. Parent, West Lafayette, IN (US);

Assignee:

Exelixis, Inc., Alameda, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 215/48 (2006.01); A61K 31/47 (2006.01);
U.S. Cl.
CPC ...
C07D 215/48 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present invention relates to crystalline forms of the free base of the c-Met inhibitor, Compound 1. The invention also relates to crystalline forms of salts of Compound 1. The invention also relates to pharmaceutical compositions comprising the solid polymorphs of the free base and salts of Compound 1. The invention further relates to methods of treating a disease, disorder, or syndrome mediated at least in part by modulating in vivo activity of a protein kinase.


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